Psoriasis - Stop Itching and Flaking

Help Heal Psoriasis with BioHeal

BioHeal can help heal the itchy, scaly, flaking patches that plague those with psoriasis. While not a cure, BioHeal improves skin health and is far safer than coal tar and other commonly used, but highly toxic, pharmaceutical drugs.

BioHeal for Improving the Health of Psoriatic Skin Many customers who have skin problems associated with psoriasis have reported that BioHeal alleviates much of the itching and flaking of psoriasis and also improves the health of their skin. In some cases, the use of BioHeal results in a complete remission of the problems of psoriasis.

BioHeal is exceptionally safe and a sharp contrast to the inadequate treatments such as psoralens (coal tars) and ultraviolet light used by many dermatologists.

Caution: BioHeal is designed to improve skin health but is not a substitute for regular skin care and medical care by a physician or other qualified health care professional.

Copper peptides stimulate skin repair, are strong Nottingham, and inhibit the production of TGF beta. (See Copper Peptide Regeneration) However, psoriasis seems to be due to an overproduction of TGF alpha and this causes an excessive proliferation of certain types of skin cells.

It is possible that copper peptides do inhibit the production of TGF alpha although this has not been studied.

In addition, psoriasis is somewhat akin to the growth of thickened skin lesions caused by excessive sun damage to the skin. BioHeal works well to help reduce such lesions (actinic keratosis) and may act in a somewhat similar manner on psoriatic lesions. Many researchers have commented that psoriasis is similar to a defective response of the skin to injury as is the skin's response to sun damage. Instead of normal cornification of the outer skin layer, the mitotic rate (cell division rate) in the epidermis increases to five times its normal level and forms a thickened pathologic stratum corneum.

Psoriasis lesions, although they are thicker than normal skin, are not an adequate skin barrier and are characterized by excessive water loss which produces an dry and itchy skin. BioHeal's skin barrier repair properties may help repair the damaged skin barrier and restore a more normal skin function. Also, psoriasis may be triggered by hyperactive immune cells called T-cells which secrete inflammatory molecules. In the studies of nickel allergy patients, BioHeal was found to have a strong anti-inflammatory action and reduce the a type of skin erythema that is similar to that observed in psoriatic lesions. This anti-inflammatory action could be due to the superoxide dismutase-like action of the copper-peptides in BioHeal.

1. Apply a light coating of the cream to the affected skin area in the morning and evening. The creams work best without any other covering or bandage.

2. You should see some improvement in skin health in a week. However, about four weeks are needed for a significant improvement in your skin’s health. Keep in mind that most medical treatments only see results on psoriasis after two to four months.

Researchers at the Harvard Medical School have recently discovered that psoralen, another ultraviolet light-activated free radical generator, is an extremely efficient carcinogen. They found that the rate of squamous cell carcinoma among patients with psoriasis, who had been repeatedly treated with UVA light after a topical application of psoralen, was 83 times higher than among the general population (Stern, Robert S. and Laid, Nan. The carcinogenic risk of treatments for severe psoriasis. Cancer, Vol. 73, No. 11, June 1, 1994, pp. 2759-64).

Many synthetic retinoids used for psoriasis should not be administered to women planning future pregnancies.

Immunosuppressive drugs such as corticosteroids, methotrexate, hydroxurea and cyclosporin A can thin the skin, have toxic effects on the liver and kidney, and decrease the production of oxygen-carrying red blood cells, infection-fighting white blood cells, and clot-enhancing platelets.

If you are not satisfied with BioHeal for improving the health of "at-risk" skin, return the unused portion within 30 days of purchase for a full refund.

Purified water, squalane, octyl palmitate, glycerol stearate, PEG-100 stearate, cetyl alcohol, copper peptides (hydrolyzed soy protein plus copper chloride), stearic acid, allantoin, camphor, menthol, diazolinydinyl urea, methylparaben, propylparaben, tocopheryl acetate.

Caution: BioHeal is designed to improve skin health but is not a substitute for regular skin care and medical care by a physician or other qualified health care professional.

From:
Prof. DiJun Rong
Sectional Chief of Clinical Departments
Zhong Shan Hospital
Shanghai Medical University
Shanghai 200032, People's Republic of China

BioHeal cream was tested on four patients with chronic eczema and two patients with psoriasis. BioHeal was compared to a urea-based cream that was applied to lateral lesions on the same patient.

In the eczema patients, the cream was very effective in reducing the thickness and itching of the lesions. In the psoriasis patients, the thickness of the lesions was thinned significantly , itching was reduced, and the quality of the skin improved although pigmentation was unchanged.

There was no evidence of adverse actions of the creams on the skin and all blood and urine tests were normal.

Last spring I began using Skin Bio products to help my eczema/psoriasis problem ( I don't know which - the dermatologist just shrugged and handed me an emollient sample ) on my scalp. Because of my condition which caused patches of inflamed areas sometimes with tiny points of bleeding and scabs, I was unable to go to a hairdresser. They of course have health regulations which restrict them from cutting hair when there is broken skin.

After two months of regular use of the Skin Bio shampoo, Bioheal and/or CP serum on my scalp ( I used the sample size of Folligen Lotion and the sample size of Emu Oil but Bioheal and CP Serum regularly ) my scalp had no reddish inflamed areas nor any broken skin. I was able to go to the hairdresser for a professional cut for the first time in four years. It was very gratifying for me so I wanted to encourage others.

My scalp is not cured because I still have areas where my hair growth is not normal - only about half an inch long - but my hair is thick enough to cover it.

I had gotten my order for FOLLIGEN last tuesday and check this out. i had suffered psoriasis on my scalp including a psoriasis mark on my right widow's peak. after using your product ITS GONE. i am still tripping over that.

I am 75 and had a patch of psoriasis on the side of one eye for years. Dermatologists gave me medicines for years without success. Four nights of the Emu Oil for Skin cleared the psoriasis.

I also have used the CP Serum followed by the Emu Oil for several weeks and the pores on my face are much smaller and hardly noticeable.

My father used Bioheal for his psoriasis and it cleared up in three days. He had previously used medicines that didn't work, and then a salicylic acid cream that only caused bleeding from his legs.

I had a psoriasis patch on my leg about three inches in diameter for several years. BioHeal removed the patch in one month and when it starts to return I put the cream on for a few days and it is gone.

Hello there, Dr. Pickart!

I haven't written you for some time, but I wanted to let you know that P&R Light has virtually eliminated my mother's psoriasis. It is truly amazing -- she had a large patch on her right forearm that was constantly irritated from rubbing against the armrest of her wheelchair, and nothing was helping, so I gave her a tube of the Light version. It showed immediate improvement, so when she finished one tube, and the psoriasis was diminished by about 50%, we got her another tube right away. Once that one was finished, there was just a light trace left, and we ordered a 4 ounce tube. She's barely gotten started on that one, and it's practically gone! What's really impressive to us is that P&R worked even during a very stressful period of time for her (and stress is a notorious trigger for psoriasis). She will never be without your product again!

Skin Biology Comment - P&R Light was a previous copper-peptide cream that has now been replaced with Protect & Restore Classic, Protect & Restore with High Retinol, TriReduction cream, or BioHeal cream...If you are not sure which cream is best for your skin type - CONTACT SKIN BIOLOGY directly.

Hello!
The BioHeal tamed down my psoriasis in about three weeks. Good product!

My dad and aunt have been using BioHeal cream and can't believe how good it works. They have problems with eczema and psoriasis. They want to order more. Send me the an order form.

As always, thanks for your excellent products and service. My mother uses the P&R Light cream on her psoriasis, and it is more effective than even her prescription medications.

The BioHeal has completely cleared my psoriasis. Every so often it pops up again and the cream stops it quickly. its almost like my problems are gone.

Just to let you know that P&R #2 is taking away a lot of the itching and flaking. Not a cure but it is so much better.

I'm re-ordering the Bioheal cream. It took about 10 days but it is definitely reduce my skin lesions. You said it was not a cure but it is still helping a lot.

Feeling much better. My skin's flaking and itchiness is greatly diminished. The lesions are much thinner and have less color. Some areas of the skin are looking nearly normal.

The skin lesions - psoriasis - are much improve and less troublesome and bothering.

It’s all Greek to me! The term, psoriasis, derives from a Greek term ‘psora’ which stands for the bran-like scaling on skin.

This unpleasant chronic skin disease, characterized by itching, scaling and inflammation, plagues all age groups. Psoriasis develops red patches of thick lesions covered with silvery scales. Not a pretty sight! The reddening of the skin, ‘erythema’, is caused by inflammation and accompanies peeling, ‘desquamation.’ Although the lesions may come and go, they are usually chronic.

Skin inflammation which extends to the upper most layer of the dermis causes the epidermis to thicken resulting in acanthosis. If immune cells penetrate inflamed skin, vesicles and pustules develop to produce scaling of the top skin layers and thereby redden the skin.

Psoriasis destroys the skin's protective skin barrier, thus allowing the skin to lose fluids and nutrients. This can also make you susceptible to infection. To some extent you can think of psoriasis as a bad sunburn that damages your skin with an overproduction of skin cells. These cells produce a thickened but dysfunctional lesion which can itch, bleed and flake off. The loss of the skin’s moisture through the lesions dries the skin. Although the lesions are thicker than normal skin they are far more porous to water and other penetrating agents. Psoriatic skin lesions contain higher levels of arachidonic acid than healthy skin. This undesirable fatty acid increases the levels of an inflammatory molecule called leukotriene (LTB4). Dietary supplements and healthy fats can help reduce inflammation. Quercetin blocks these inflammatory mediators by down regulating the 5-lipoxygenase pathway and reduces inflammation. The involvement of the fatty acid, arachidonic acid, in the biochemical pathways of skin inflammation has led to the discovery of modestly-effective dietary therapies using essential fatty acid such as gamma-linolenic acid (GLA from primrose oil and borage oil) and eicosapentenoic acid (EPA from fish oil) However, some nonsteroidal anti-inflammatory drugs such as indomethacin may worsen psoriasis.

If you suffer with psoriasis, you may notice times when your skin worsens and then suddenly improves. Conditions that may cause flare-ups include changes in climate, infections, stress, and dry skin.

Psoriasis often flares up on the elbows, knees, scalp, face, palms, and soles of the feet. It may also inflame fingernails, toenails, and the tissues inside the mouth and genitalia. Additionally, the skin on joints can crack. About 10 percent of psoriasis patients experience symptoms of arthritis in their joints.

Psoriasis Vulgaris: the most common form of psoriasis (commonly referred to as Plaque Psoriasis). The markers for Psoriasis Vulgaris are lesions with a reddened base covered by silvery scales.

Guttate Psoriasis: drop-like lesions on the trunk, limbs, and scalp. Guttate Psoriasis may be triggered by viral infections or certain bacterial (streptococcal) infections.

Pustular Psoriasis: forms blisters of noninfectious pus on the skin. It may be worsened by medications, excessive sunlight, infections, pregnancy, emotional stress, or exposure to contact irritants.

Inverse Psoriasis: forms dry, smooth, red plaques that occur in the folds of skin under the breasts, in the armpits or near the genitals.

Erythrodermic Psoriasis: causes widespread reddening and scaling of the skin, itching and pain. It may be triggered by severe sunburn, use of cortisone or corticosteroids.

The following medical treatments tend to be inadequate, toxic and often rely upon simplistic research.

Mild cases of psoriasis are usually treated with lubricating creams and oils alone or with corticosteroids containing cortisone-like compounds (which actually increase skin damage), salicylic acid, crude oil tars, or anthralin synthetic vitamin D. These are often used in combination with natural sunlight. General recommendations include avoiding (1) trauma to the skin; (2) severe sunburn; (3) topical medications such as lithium and hydrochloroquine and (4) systemic corticosteroids.

Coal tar is applied directly to the skin, used in baths and shampoos for the scalp. Although coal tar makes skin more sensitive to ultraviolet (UV) light, it is used with phototherapy which can irritate the skin. Coal tar has fewer side effects than corticosteroids but is less effective. Anthralin, purified from coal tar, is used to treat chronic psoriasis lesions, however it often irritates the skin and is only marginally effective.

Salicylic acid helps remove scales and is often combined with topical steroids, anthralin, or coal tar.

Moisturizers have a cosmetic and soothing effect but may further loosen and damage the skin. The damaged skin barrier in the lesions rapidly exudes water and dries the skin. Moisturizers that are thick and greasy usually work best.

Retinoids include compounds similar to vitamin A (retinol) and retinoic acid (Retin-A and Renova) which are both safe effective compounds. However, psoriasis is often treated with synthetic retinoids which pose dangerous side effects. Synthetic retinoids include etretinate (Tegison) and isotretinoin (Accutane). Etretinate is most effective against pustular and erythrodermic psoriasis. Isotretinoin is also helpful against pustular psoriasis. Tazarotene (Tazorac gel) is a new topical developed for psoriasis. For women of child-bearing age, Etretinate and Acitretin, is currently available but should not be administered to women planning future pregnancies. The FDA recommends that women stop taking them three years before conceiving. Acitretin (Soriatain) is a retinoid that is quickly eliminated from the body. Many psoriasis treatments are dangerous for women and their children and pose the possibility of causing birth defects. Retinoid treatments are often combined with ultraviolet therapy. (Verschoore 1993)

Vitamin D analogs are based on the positive effect of sunlight on psoriasis and the effects of sunlight on vitamin D synthesis and metabolism. A vitamin D derivative, vitamin D3 or 1,25 dihydroxycholecalciferol (Calcipotriol or Calcipotriene), normally produced by the liver and kidneys, appears to be useful for people with psoriasis. This is a prescription drug and over the counter vitamin D is ineffective. D3 may work by reducing cell proliferation and by suppressing immune cell activities. (Kragballe 1993).

Vitamin D can act by inhibiting a cytokine cascade involved immune cells that produce the inflammatory cytokine interleukin 8. Vitamin D3, taken orally (400 mg/day) or topically (10mg/gm), decreases skin cell proliferation by decreasing the skin cells’ sensitivity to growth factors. Calcipotriene is incorporated into ointment such as Dovonex and applied twice daily. Calcipotriene may irritate the skin and is not recommended for the face or genitals. Skin improvements are seen in 60% of patients after four months.

Sunlight and ultraviolet light are used with psoralen (PUVA) for severe cases of psoriasis. Dithranol, as a pretreatment in PUVA, has shown recent therapeutic promise (Rogers, 1993). Researchers at Harvard Medical School have recently discovered that psoralen, another ultraviolet light-activated free radical generator, is an extremely efficient carcinogen. They found that the rate of squamous cell carcinoma among patients with psoriasis, who had been repeatedly treated with UVA light after a topical application of psoralen, was 83 times higher than among the general population.

UVB Phototherapy uses artificial light. This type of phototherapy is normally administered in a physician’s office. UVB phototherapy may be combined with other treatments such as a coal tar bath and an application of an anthralin-salicylic acid paste, which is left on the skin for 6 to 24 hours.

PUVA treatment combines oral or topical administration of a drug called psoralen with exposure to ultraviolet A (UVA) light. Psoralen makes the body more sensitive to UVA light. PUVA normally clears lesions more rapidly than other methods. However, it is associated with increased side effects, including nausea, headache, fatigue, burning, itching and irregular skin pigmentation. Researchers have found that PUVA is effective and relatively safe when combined with other medications such as retinoids and hydroxyurea.

Immunosuppressive drugs include corticosteroids, methotrexate and cyclosporin A.

Corticosteroids applied twice each day, although often effective, can lead to adverse side effects. Some physicians use high-potency corticosteroid ointments (such as Diprolene, Temovate, Ultravate, or Psorcon). Long-term use of high-potency steroids can lead to thinning of skin, internal side effects and worsening of the psoriasis.

Methotrexate and Cyclosporin A (Wong et al, 1993) have proven reasonably effective but are restricted to severe psoriasis because of the drugs’ toxic effects to the liver and kidney. Methotrexate can cause liver damage and decrease the production of oxygen-carrying red blood cells, infection-fighting white blood cells, and clot-enhancing platelets. Methotrexate should not be used by women who are pregnant, planning to get pregnant, or their male partners. A new drug, Novartis Pharmaceuticals Corp.’s Neoral(R) (a cyclosporine emulsion), is effective for severe plaque psoriasis. It relieves many symptoms such as pain, itching, scaling and irritation.

Hydroxyurea (Hydrea) is less toxic than methotrexate but also less effective. Hydroxyurea is sometimes combined with PUVA or retinoids. Side effects include anemia and decreases in white blood cells and platelets. Like methotrexate, hydroxyurea should be avoided by women who are pregnant or planning to get pregnant

Sunlight and UV light - even without the dangerous coal tars and psoralens - is an effective treatment for psoriasis. Reports indicate that 80 percent of those suffering from this skin disease improve when they are exposed to UV light.

Natural sunlight can significantly improve, or clear psoriasis. Regular daily doses of sunlight taken in short exposures are recommended. UV light from the sun stimulates production of vitamin D by the skin, which slows the overproduction of skin cells that causes scaling. Avoid sunburn which may make psoriasis worse. Be aware that it can take several weeks to see improvement.This natural approach to treating psoriasis is often referred to as climatotherapy. Some people travel to Florida, Hawaii, or the Caribbean to enjoy swimming and natural sunlight as their psoriasis treatment. The most recognized site for climatotherapy, the Dead Sea in Israel, offers treatment solariums with supervised medical assistance.

While many dermatologists admonish psoriasis patients to only use prescription tanning devices combined with photosensitizing psoralens (psoralens increase skin cancers approximately 80-fold), there is evidence that commercial tanning bed therapy is effective. In a six-week study of 20 patients with stable psoriasis vulgaris, patients received three to five tanning sessions per week in commercial tanning beds without psoralens. The ultraviolet dosage was adjusted to just be below the amount required to produce erythema (redness) of the skin. All patient demonstrated benefit from the tanning beds with the average Psoriasis Area Severity Index dropping from 7.96 to 5.04. (Fleischer et al 1997).

Dietary fats such as omega-3 long-chain fatty acids reduce psoriasis in some patients. (Collier et al 1993, Soyland et al 1993) A British study controlled study found that eating 170 grams of oily fish daily for 6 weeks reduced the severity of psoriasis. Fish oil is high in the polyunsaturated omega-3 fatty acids, eicosapentanoic (EPA) and docosahexaenoic acids (DHA). EPA competes with a highly inflammatory acid, arachidonic acid (AA), for metabolism by the cyclooxygenase and lipoxygenase pathways. EPA, an anti-inflammatory fatty acid, replaces AA and there is less skin inflammation. Studies on fish oil reported some improvements after two to three months. Such studies used about 1.8 grams of EPA per day which may require taking 10 grams of salmon oil. A higher amount 3.6 grams of EPA per day was found to reduce psoriasis symptoms by 50% after five months of supplementation. Some research suggests that it may be possible to apply fish oil topically and still psoriasis improvement.

Holistic medicine offers an attractive and gentle option for treating psoriasis. For example, Dr. Andrew Weil recommends using natural sunlight on the affected area, taking high levels of antioxidants such as beta carotene, Vitamin C, Vitamin E, and selenium, plus milk thistle seeds (silymarin) at 300 mg daily. Some practitioners also recommend Folic Acid, Vitamin A, B12, Selenium, Zinc, Glucosamine, Essential Fatty acids, and Lecithin.

Bathing in oil offers a luxurious approach to treating psoriasis. Many find that adding oil to a warm bath and then following up with a moisturizer soothes their skin. Scales can be removed and itching reduced by soaking 15 minutes in water containing a tar solution, oiled oatmeal, and Epsom salts.

Some people may recuperate on a hypoallergenic diet. One study reported that eliminating gluten (found in wheat, oats, rye, and barley) improved psoriasis.

Fumaric acid ester is occasionally taken as a supplement and has successfully treated psoriasis in some studies. (Kolbach and Nieboer 1992)

Cayenne contains a substance known as capsaicin that acts on sensory nerves to decrease pain and itching. Creams containing 0.025-0.075% capsaicin are generally applied. There may be a burning sensation which decreases with each use.

Burdock root has been used both internally and externally for psoriasis. Herbalists recommend 2-4 ml of burdock root tincture or 1-2 grams of dried root daily as a capsule. In large quantities, burdock root may stimulate the uterus and should not be used during pregnancy.

Milk thistle seeds are considered very safe. Herbalists recommend 420 mg of silymarin daily from capsules. Once improvement is noticed at about two months, lower the dosage to 280 mg per day. If taking raw seeds, eat 12-15 grams of milk thistle seeds daily or drink them in a tea. Sarsaparilla has been used as an anti-inflammatory and the dosage is at least 9 grams of the dried root daily, usually divided between morning and evening.

Sarsaparilla can cause nausea and kidney damage and large doses for long periods of time should be avoided.

Bitter melon inhibits the enzyme guanylate cyclase, which may benefit people with psoriasis. Small children or anyone with hypoglycemia should not take bitter melon since it may lower blood sugar. Diabetics taking hypoglycemic drugs (such as chlorpropamide, glyburide, or phenformin) or insulin should use bitter melon only under medical supervision.

Whole Oregon grape extracts were shown in one study to reduce the inflammation associated with psoriasis. Barberry, similar to the Oregon grape, is also used. Ointments containing these extracts are applied about three times per day. Oregon grape, barberry, and other berberine-containing plants should be used with caution during pregnancy and while breast-feeding.

Quercetin, a plant flavinoid, blocks the 5-lipoxygenase pathway and reduces inflammation. It is very safe and the average daily intake is 25 mg in the United States.

1. Keep the skin supple and enjoy regular oil baths, e.g., one teaspoon of GLA/EFA oil, or apply GLA/EFA to the lesion.

2. Apply anti-inflammatory cream, e.g., MPS Exfolia, to the lesion. This cream contains mucopolysaccharide, vitamin A, E, B6, biotin and essential fatty acids. The topical application of these nutrients will increase the rate of healing as well as decrease inflammatory responses. The application of GLA/EFA will also increase healing.

3. Take linseed oil (1-2 tablespoons per day) or supplement with GLA/EFA (3 teaspoons per day).

4. Improve the absorption of nutrients by supplementing with digestive enzymes at each meal (DEF or Hydrozyme).

5. Increase intake of fish oils, particularly those rich in EPA, e.g., wild salmon, sardines, or mackerel, as well as onions and garlic.

6. Avoid smoking or being passively exposed to cigarette smoke, as the nicotine in the smoke can initiate seborrheic dermatitis and thus complicate the psoriasis in some sensitive individuals.

7. Check for drug sensitivity, particularly to beta-adrenergic blocking drugs that are used in the treatment of blood pressure.

8. Avoid stressful situations, fatigue, environmental change (such as exposure to cold) and trauma to the skin as these can initiate new skin lesions.

9. Many drugs can initiate or aggravate psoriasis in susceptible individuals. These are alpha interferon, cortisone, lithium, phenylbutazone, aspirin, progesterone, iodide, nystatin, indomethacin and beta-blockers. Care must be taken when taking these drugs.

10. Inhibitors of phosphodiesterase (eg. Quercetin, theophylline) which increase cAMP levels can improve psoriasis.

11. Vitamin A inhibits ornithine decarboxylase and thus reduces the formation of polyamines. This reduction results in decreased cellular proliferation.

12. Taking the enzymes, trypsin, chymotrypsin and pancreatin (DEF), one hour before meals can reduce circulatory kinins or inflammatory mediators.

Lymphodran
     3 - 4/day (Regulates Calmodulin Leukotrienes)
GLA/EFA
     1 - 2 tsp/day (Anti-inflammatory) apply to the skin lesion as well
BACE
     3 - 8/day, depending on severity (Anti-oxidant)
DEF
     1 - 2/1hr prior to meal (Reduces Allergen load\ Improves digestion)
Hydrozyme
     1 tablet with meal (Improves digestion)
Kelamin
     2/day (B complex)
Heme 100
     2/day (Folic Acid, B12 supplement)
C powder with Bioflavonoids
     1 - 3 teaspoons/day (Improves wound healing)
Glucosamine
     4 - 6/day (Improves ground substance viscosity)
Lecithin Granules
     1 dessertspoon/day (Inositol pathway regulation)
D alpha tocopheryl succinate 632 mg 1 - 2/day (Regulator of inflammatory cycle)
Comment - Mixed isomers in natural tocopheryl (alpha, beta, gamma, delta) would probable be better.
SAD
     1 - 4/day, empty stomach (Decrease anxiety and tension)
SFM
     1 - 3/day, empty stomach (Reduces stress)
MPS Exfolia
     Apply to the skin morning and night.
Vitamin D
     400 - 800 I.U./day

Scientific Literature References

Collier et al 1993 - Collier, Ursell, Zaremba, Payne, Staughton, and Sanders, 1993. Effect of regular consumption of oily fish compared with white fish on chronic plaque psoriasis. European Journal of Clinical Nutrition, volume 47, pages 251-254.

Fleischer et al 1997 - Fleischer et al 1997 Commercial tanning bed treatment is an effective psoriasis treatment, J. Invest. Derm. 109:170-174, 1997.)

Kolbach and Nieboer 1992 - Kolbach DN, Nieboer C. Fumaric acid therapy in psoriasis: results and side effects of 2 years of treatment. J Am Acad Dermatol volume 27:769-71.

Kragballe 1993 - Kragballe and Iversen, 1993. Calcipotriol: a Clinics, volume 11(1), pages 137-141.

Rodgers, 1993. Measurement of plaque thickness and evaporative water loss in psoriasis with PUVA and dithranol treatment. Clinical Experimental Dermatology, volume 18(1), pages 21-24.

Soyland et al 1993 - Soyland E, Funk J, Rajka G, et al. Effect of dietary supplementation with very-long-chain n-3 fatty acids in patients with psoriasis. N Engl J Med 1993;328:1812-6.

Stern et al 1994 - Stern, Robert S. and Laid, Nan. The carcinogenic risk of treatments for severe psoriasis. Cancer, Vol. 73, No. 11, June 1, 1994, pp. 2759-64.

Wong et al 1993 - Wong, Winslow, and Cooper, 1993. The mechanisms of action of cyclosporin A in the
treatment of psoriasis. Immunology Today, volume 14, pages 69-74.

Verschoore 1993 - Verschoore, Bouclier, Czernielewski, and Hensby, Topical retinoids: their uses in dermatology. Dermatologic Clinics, volume 1, pages 107-115.

Product	Price
BioHeal (1.7 oz)	19.95

Product	Price
BioHeal (1.7 oz)	19.95