Skin Biology Help and Index to Products and Information
 

BioHeal for Diabetic Skin Problems

If you are a diabetic, you may have suffered from chronic sores that never seemed to heal. Perhaps you live under a cloud of fear that infection may one day lead to amputation. Let BioHeal dispel the anguish. BioHeal can come to your rescue and nurse your skin back to health.

Our diabetic clients, those who often experience slow and inadequate skin repair, are some of the happiest BioHeal customers. Their skin complications lead to dry skin that tends to crack and heals at a snail’s pace. Leg and foot sores are the leading cause of lower leg amputations. Approximately 10% of diabetics require an amputation during their lifetime due to infections associated with broken and ulcerated skin. Diabetics have 15 times the average risk for experiencing limb amputations.

Many BioHeal users tell us that when they apply BioHeal to their sores, they notice a rapid improvement in their skin health. Most diabetics observe that the product helps prevent cracks and fissures that would normally lead to skin ulcers. And that’s good news! By rapidly healing broken and cracked skin before an infection sets in, diabetics can stave off this leading cause of amputations and death.

Product	Price
BioHeal (1.7 oz)	19.95

 
So as you can see, there is no need for doom and gloom. Diabetics can find it fairly easy to heal much of their skin damage. By pre-washing sores with 3% hydrogen peroxide followed by applications of copper-peptide cream, the skin can heal beautifully. In the adjacent photo, a diabetic women had six skin ulcers on her foot. Physicians recommended immediate amputation. Instead she tried the hydrogen peroxide washes followed by applications of BioHeal to the periphery of the skin ulcers. Photos to the far left illustrate either side of the foot prior to this procedure and those to the right show a remarkable recovery after just 28 days of hydrogen peroxide and BioHeal. After 28 days all the skin ulcers healed. The ulcers never re-occurred and she only used additional BioHeal as needed when her skin became excessively irritated and cracked.

For cracked skin, apply a light coating of BioHeal once daily as needed. For skin ulcers, put the BioHeal around the edge of the ulcers. This aids in healing the outer edge of the ulcers. BioHeal is not FDA-approved for use within the ulcer area.
 
 
 
 
 
 
 
 
 

Some clinicians advise against the use of hydrogen peroxide, stating that it increases skin damage. However, our reviews of the medical literature have found many reports of improved skin healing after washes of hydrogen peroxide at low concentrations (1% to 10%). However, skin damage occasionally occurs at higher concentrations. So it would be prudent to apply hydrogen peroxide at concentrations of 1 to 3% and no higher.

BioHeal rapidly improves skin health in many who are at risk for skin ulcers and bedsores. Not only that, the product stops future sores in their tracks. Prevention is the key -- much better than healing open skin wounds.
 

Caution: BioHeal is designed to help maintain and improve skin health but is not a substitute for regular skin care and medical care by a physician or other qualified health care professional.

 
 
 
  
 
 

Skin Biology Products for Diabetic Skin Conditions

Name	Best uses
BioHeal	Effective repair cream
CP Serum	Often works well on eczema
Emu Oil S Lipid Replenisher for Skin	Helps moisturize dry, cracking skin

Product
BioHeal, 1.7 oz, $19.95
CP Serum, 4 oz. bottle, $40.95
CP Serum, 1 oz bottle, $22.95
Super GHK-Copper Serum, 15ml - First Generation GHK-Copper Complex,  $39.95  READ MORE ABOUT SUPER GHK-COPPER
Super GHK-Copper Serum, 50ml - First Generation GHK-Copper Complex,  $99.95
Super GHK-Copper Cream, 15ml - First Generation GHK-Copper Complex,  $39.95
Super GHK-Copper Cream, 50ml - First Generation GHK-Copper Complex,  $99.95
Emu Oil S Lipid Replenisher for Skin, 2 oz,  $29.95 Peroxide free supplemented with CoQ-10, tocotrienol family, tocopherol family, leutin, and lycopene. To replenish depleted skin lipids in dry or damaged skin.

Caution: BioHeal is designed to improve skin health but is not a substitute for regular skin care and medical care by a physician or other qualified health care professional.

Product Ingredients

BioHeal Product Ingredients - Purified water, squalane, octyl palmitate, glycerol stearate, PEG-100 stearate, cetyl alcohol, copper peptides (hydrolyzed soy protein complexed with copper chloride), stearic acid, allantoin, menthol, diazolinydinyl urea, methylparaben, propylparaben, camphor, menthol, tocopheryl acetate.

BioHeal Testimonials

G.P.
Minnesota

I have a (diabetic) friend (in her 80s) who still had two open sores from an operation a year ago. So I gave her my tube of BioHeal a month ago. Yesterday she called and said the sores were totally healed

F.J.
Minnesota

Skin Biology:

The BioHeal has really helped with my diabetic skin skin problems. When a spot of my skin starts looking bad, I put on Bioheal for a few days and it looks good as new.

Bless you,

A. H.

Pittsburgh, PA

My mother has diabetes and is in a wheelchair. She gets sores on her face and limbs.
The BioHeal is working very well to quickly heal the sores.

G.R.
Washington State

I used BioHeal® on my mother's open skin sore and it healed it.

Thank you for the product!

K.S.
Bridgeport, CT

I am a paraplegic and a diabetic. This combination presents too many cases where I have varying types of sores, from small to large, which take a much longer time to heal, since I became a diabetic some 6 years ago. I was given your product to try out around a decubitus ulcer which I had on my left side of my rump where the bone protrudes closest to the skin , while in a seated position. These sores appear quite often for spinal cord injured persons. They can take as long as 6 months to heal, which means a person usually must stay off of it for that entire period of time.

I used the blue ointment of yours (BioHeal), as directed, a thin layer around the wound. We had started to use a product called COMFEEL which I believe is put out by SQUIBB, which has worked reasonably better than what I have used in the past. At first, the sore was weepy, and that dressing would not stay put for more than a day at a time. As we continued to use it, it lasted for longer periods of time. Finally, after a couple of weeks of this procedure, we introduced your product. It wasn't a couple of days before it was healed after that. Please understand, we continued to use the SQUIBB COMFEEL patch, but added your product.

In addition to that, I often gouge my shins or varying things, related to my doing tasks necessary for my catering business, and with my feet projecting in front of me, being seated in a wheelchair, it makes it difficult to always reach items which I need. Since I have no sensation below the waist, I'm usually not aware that I even have a problem until the evening when I undress, and see the damage. This has happened twice since I started using your ointment (BioHeal). I have been amazed to see my more surface sores heal in a matter on about one week, where before it would take several weeks or longer.

Sincerely,

Dale Lundgrun

P.S. I am the former president of the Board of Directors of the Sister Kenny Institute in Minneapolis.

Dear sirs:

The blue ointment is keeping my feet very healthy. There is no more cracking of the skin and the skin looks very good.

S.M.
Ohio

BioHeal is solving my dry skin problems associated with diabetes. I no longer have to use moisturizers.

M.T.
California

My husband is diabetic and has an amputated limb. The skin kept getting raw and sore at the end but now the BioHeal cream is keeping the skin very healthy.

Thanks,

M.G.
Illinois

From the Wichita Eagle,
May 1, 2001

It Worked for Me

Name: Joy Dawson, Wichita.

Personal: 75, single, middle school substitute teacher.

Problem: Eczema, a painful skin inflammation, on her index fingers and thumbs.

What she did: tried a copper-peptide lotion (CP Serum) meant to be a skin care product, after reading a newspaper story about non-surgical ways to reduce wrinkles.

She had unsuccessfully tried lotions and salves from her dermatologist and was wearing gloves on her hands at night at the suggestion of her son who's a doctor.

How She did it. Dawson's hands were so affected that "there would be cracks and splits, and they'd be bleeding."

The story about copper peptide creams mentioned that copper peptide creams were originally developed for burn victims and diabetics whose wounds wouldn't heal. Dawson has type 2 diabetes, which often can be controlled with diet and medication rather than insulin.

Small studies had shown that skin treated with copper peptides had less pigmentation, reduced wrinkling, and held more moisture.

Dawson had tried alternative medicine in the past and wasn't finding relief from other sources, so she didn't have to think long about trying the copper peptide lotion, which she ordered from the Internet.

Dermatologists' offices sell copper peptide products; they're also available over the Internet through companies including Neova and Skin Biology.

She hasn't tried the lotion on her face: She jokes that she's to old for it to do much good.

Alpha Lipoic Acid, a universal and powerful antioxidant for diabetics, provides an extra surge of antioxidant protection; like a light bulb, it fuels an energetic jolt to synergistcally enhance other antioxidants. This vitamin-like substance, (also called Thioctic Acid or Lipoic Acid), can counter cellular damage in Diabetics and in anyone who wishes to slow down aging and burn fat. According to Richard A. Passwater, Ph.D., in his book Lipoic Acid: The Metabolic Antioxidant, Alpha Lipoic Acid neutralizes free radicals, protects the body's genetic material, slows aging, and protects against heart disease and cancer. During aging a protein called NF-kappa-B builds up in the cells and binds to the DNA and slows DNA function. As a result, the immune system weakens, skin ages faster and body systems deteriorate, no longer functioning in a vital state. Alpha Lipoic Acid (and also glutathione/reduced glutathione) help block the binding of NF-kappa-B to cellular DNA. This results in a younger and less wrinkled skin. In animals, Alpha Lipoic Acid has anti-atherosclerotic effects.

Diabetics are at risk for heart disease in part because they have a faulty energy metabolism which results from their inability to utilize glucose efficienty. Heart disease is associated with how well heart cells produce energy. Alpha Lipoic Acid can help in this regard since it produces ATP, the body's energy transferring molecule. When producing ATP from glucose, a molecule called Acetyl Co A generates and creates ATP through the Krebs cycle. Alpha Lipoic Acid, a necessary co-factor in many of Krebs cycle reactions, can increase cellular energy production. Since one of the key characteristics of aging is a sharp fall-off energy, Alpha Lipoic Acid may help all of us lead a longer more energetic life. According to Dr. Hans Tritschler, a scientist in Munich, Germany, supplemental Alpha Lipoic Acid can increase ATP production from glucose by approximately 40%. Furthermore, this increases the body's burning of fat since fax oxidation requires metabolism intermediates produced by the burning of glucose. An old biochemical adage is "Fat burns in the flame of the sugars."

Since Alpha Lipoic Acid is a universal antioxidant, soluble in both fat and water, it interacts with other antioxidants such as vitamins E (fat soluble) and C (water soluble) and glutathione; it synergistically helps to regenerate them. Most antioxidants get destroyed in the process of deactivating tissue-damaging oxidative agents. However, Alpha Lipoic Acid can regenerate and recycle antioxidants, providing a powerful punch to oxidative damage. Alpha Lipoic Acid recycles ascorbic acid (vitamin C). When ascorbic acid takes electrons from a free-radical, it turns into a dihydroascorbate. When dihydroascorbate encounters available Alpha Lipoic Acid, the kidneys will excrete the dihydroascorbate into the urine, thereby robbing the body of its benefits. Alpha Lipoic Acid also recycles the tocopherols (Vitamin E) and Glutathione by acting as a "Redox" (reduction-oxidation) agent. Very few substances can perform this recycling function and, in this way, Alpha Lipoic Acid multiples the effectiveness of other antioxidants.

The elevated body sugars associated with diabetes increase the tissue damaging process called glycation, a process in which sugars in the body bind to proteins and damage the proteins. Glycation occurs when portions of glucose molecules attach to issue proteins and producing Advanced Glycosalation End-products (AGE). This glycation damage sometimes ruptures tissue, producing dysfunctional or dead cells with reduced tissue integrity. This type of damage is cumulative and is the principal cause of the progressive tissue damage of diabetes and one of the ways that muscle tissue is lost during aging.

Alpha Lipoic Acid is another protector against glycation.  European physicians use Alpha Lipoic Acid to reduce the need for injected Insulin or insulin enhancing drugs such as Glucotrol. It is used to help control blood sugar levels and reduce the glycation damage associated with primary and secondary diabetes.

Diabetic peripheral neuropathy increased risk of developing foot ulcers because of the lack of feeling in the limbs. Alpha Lipoic Acid has been reported to help regeneration of nerve cells damaged by diabetic neuropathy. It was initially thought that this was the result of Alpha Lipoic Acid reducing the progressive nerve destruction which allowed the some repair of nerves. However, Dr. Ziegler at Heinrich-Heine University reported that treatment with Alpha Lipoic Acid induced "sprouting", or growth of new fibers, in as little as three weeks which is a marked acceleration of normal nerve repair.

Cataracts associated with diabetes are caused by the degeneration of proteins in the lenses lenses of the eyes. The two principal causes are glycation of proteins and damage from ultraviolet rays of the sun. The lenses of the eyes are not well protected by anti-oxidants in blood. In 1994, Dr. Lester Packer and his group found that Alpha Lipoic Acid increased the levels of glutathione, vitamin C and vitamin E in the eye lens tissue of animals and reduced the rate of cataract formation.

Alpha Lipoic Acid has been used in Europe for more than thirty years at dosages of 300 to 600 milligrams per day for the treatment of diabetic neuropathy without noticeable undesirable side-effects.
 For more information on protective dietary supplements visit www.skinbiology.com/dietsupplements.html

Increased tissue Copper, taken as a supplement, reduces protein glycation. Copper proteins are the primary defensive anti-oxidant system in the human body.See www.skinbiology.com/copperhealth.html.

Aminoguanidine to Stop Excessive Glycosylation During Diabetes

Like Alpha Lipoic Acid, Aminoguanidine is an anti-glycosylation agent which can be obtained from vitamin stores. It may be the most potent available anti-glycosylation agent. It effectively counters the damage caused by protein cross linkages and appears especially useful preventing collagen crosslinks. Studies in animals have shown that aminoguanidine can prevent the types of molecular cross linking that occurs with diabetes, atherosclerotic plaque formation, blood vessel hardening with age, and cross linkage of brain proteins. For more information on protective dietary supplements visit www.skinbiology.com/dietsupplements.html

Iamin Gel Wound Dressing®, Iamin Impregnated Gauze Dressing®, OsmoCyte® PCA Pillow, Iamin Wet Dressing (copper-saline)®, Iamin-2 Hydrating Gel®, Iamin-Vet®, GraftCyte® Advanced Hair Restoration Technology, GraftCyte® Moist Dressings, GraftCyte® Hydrating Mist, GraftCyte® Post-Surgical Shampoo & Conditioner, GraftCyte® Head Start Single Patient Pack, Tricomin® Solution Follicle Therapy Spray, Tricomin® Revitalizing Shampoo, Tricomin® Restructuring Conditioner and Tricomin® Conditioning Shampoo, Complex Cu3® Intensive Tissue Repair Cream, Complex Cu3® Hydrating Gel, Complex Cu3® Gentle Face Cleanser, Iamin-IB® , Neova®, are trademarks of ProCyte Corporation and marketed by ProCyte and Bard Medical. Blue Copper Firming Elasticity Repair®, Climate Extreme Body Repair®, and Blue Razor Aftershave®, are  products and trademarks of Osmotics Inc. Propecia® is a trademark of Merck Pharmaceuticals. . Biopeptide-CL is a trademark of Sederma. A-Copper Moisturizer is a trademark of Serious Skin Care. Kinerase(TM) is a product and trademark of ICN Corporation. Neutrogena Visibly Firm Night Cream®, and  Neutrogena Visibly Firm Eye Cream® are products and trademarks of the Neutrogena Company.