Products Based on Integrity and True Science™ for At-Risk Skin with Damage, Sores, Itch, Rash, and Severe Dry Skin

How Skin Remodeling Copper Peptides Aid Skin Health

Healthful Action

Acts by:

Effect on Skin

Anti-inflammatory and anti-oxidant

1. Activates superoxide dismutase by supplying copper
2. Decreases production of TGF-beta and scarring caused by TGF-beta
3. Blocks skin damage by interleukin-1

Calmer skin
Less Irritation
Less scar formation

Removes damaged skin and proteins

1. Activate metalloproteinases

Removal of damaged proteins, damaged skin, and skin blemishes

Rebuilding skin

1. Help increase the synthesis of new collagen, elastin,
and water-holding proteoglycans
2. Aids in rebuilding the blood's microcirculation
3. Repairs and tightens skin barrier
4. Increases production of new skin cells

Firmer, tighter, better-looking skin
Better moisturized skin
More resistance to entry of viruses and bacteria

Studies on Dr. Pickart's skin remodeling copper peptides

Publications from over at over 30 leading Universities and Medical Research Institutes by leading dermatologists and scientists

For more on the studies,
visit Copper-Peptide Regeneration

"The Turn Back the Clock Doc", Loren Pickart has spent his life working on methods to reverse the effects of aging in the human body. His work led to the Skin Renewal Cycle and the discoverer of the role of remodeling copper peptides on the repair of human skin and other tissues such bone, hair follicles, liver, stomach lining, and the intestinal tract after his isolation of the human skin remodeling copper-peptide, GHK-Copper from human blood. Skin remodeling copper peptides are the body's natural signals that repair and restore damaged and aged tissue by (1) inducing strong anti-inflammatory actions (activate superoxide dismutase and decrease damaging actions of TGF-beta and interleukin-1), by (2) stimulating the removal of damaged and older skin by increasing the synthesis of metalloproteinases, and (3) by increasing the generation of new collagen, elastin, proteoglycans, and rebuilding the microcirculation and by increasing production of new skin cells. He and his wife, Charlene, worked to start ProCyte Corporation in 1985 to develop his first generation of GHK-Copper products and Skin Biology in 1994 to create a second generation of more effective, skin remodeling copper peptides.

Products based on Dr. Pickart's inventions are using skin renewal, improving hair growth, increasing the success of hair transplants, and after dermatological peels, laser resurfacing, and dermabrasion by many companies including AdviCare, American Crew, Amuchina (Europe), Atelier Esthetique, Bard Medical, BioPharm, Creative Nail Design, Johnson & Johnson, Schering AG, Neutrogena, Osmotics, ProCyte, Sigmacon Medical Products and Tanox Biosystems. In addition, human clinical studies of Pickart's inventions for bone healing and healing of intestinal irritations (Inflammatory Bowel Disease or Crohn's disease) have given positive results. He received his Ph.D. in Biochemistry from the University of California at San Francisco. For details on copper-peptide tissue remodeling - see: Copper-Peptide Regeneration.

Skin Biology is currently patenting and test marketing various products built around his new copper-peptides that are designed to possess greatly enhanced potency, strong breakdown resistance (and can be used with skin exfoliating hydroxy acids for more rapid skin renewal and for scar reduction), a longer duration of action, and very high adherence to skin. The first generation products designed around GHK-Copper performed well in many controlled tests; however, they failed in FDA clinical trials on the healing of difficult-to-heal human wounds. Dr. Pickart is of the opinion that this second generation of copper peptides should have a higher chance of success in difficult clinical trials.

Pickart currently is working on a theory of the biochemical mechanism of how the human body repairs damaged tissues and organs.